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目的:探讨肥胖与更年期女性乳腺癌的发病危险因素。方法:对58例女性乳腺癌患者临床资料进行分析,并与同期进行常规体检的106例健康女性做对比性分析。结果:非条件多元Logistic回归分析中,体重指数及甘油三酯组P值存在显著差异,体重增加1个等级乳腺癌危险性增加OR4.78～10.63;甘油三酯增加1个等级乳腺癌危险性增加OR5.66～8.67,随着体重指数及甘油三酯增加,随之乳腺癌危险性也呈增加趋势。结论:更年期女性乳腺癌的发病与肥胖、高甘油三酯存在正相关关系,控制高热量饮食及体重的增加,加强体育锻炼对预防乳腺癌具有重要作用。
Objective: To investigate the risk factors of breast cancer in obese and menopausal women. Methods: The clinical data of 58 cases of female breast cancer were analyzed and compared with 106 healthy women who underwent routine physical examinations in the same period. Results: There was a significant difference in body mass index and triglyceride group P value in non-conditional multivariate Logistic regression analysis. The risk of breast cancer increased by 1 to 4. The risk of breast cancer increased by 4.78 ~ 10.63. Triglyceride increased the risk of breast cancer by 1 grade Increase OR5.66 ~ 8.67, with body mass index and triglycerides increased, along with the risk of breast cancer also showed an increasing trend. Conclusions: The incidence of breast cancer in menopausal women is positively correlated with obesity and high triglycerides. It is important to control high calorie diet and weight gain and to improve physical activity to prevent breast cancer.