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目的：探讨重性精神病患者家属焦虑抑郁情绪的相关影响因素。方法采用自拟一般家庭状况调查问卷、疾病家庭负担量表、焦虑自评量表、抑郁自评量表对265名重性精神病患者家属进行测评分析。结果本组患者家属焦虑自评量表、抑郁自评量表总分均显著高于中国常模（P＜0．01）。患者病前病后家庭经济状况、家庭年人均收入、患者治疗费用报销比例均与家属抑郁严重度指数、焦虑自评量表总分呈显著负相关（ P＜0．05或0．01），患者病程、住院次数均与家属抑郁严重度指数、焦虑自评量表总分呈显著正相关（P＜0．01）；家属受教育年限与其焦虑自评量表总分呈显著负相关（P＜0．01），患者病情不稳定程度、患者年均治病费用与家属焦虑自评量表总分呈显著正相关（ P＜0．05或0．01）。疾病家庭负担量表总分及各维度分与家属抑郁严重度指数、焦虑自评量表总分呈显著正相关（P＜0．01）。结论重性精神病患者家属存在有明显的焦虑抑郁情绪问题，疾病家庭负担，尤其是经济负担是影响家属焦虑抑郁情绪的主要因素。“,”Objective To investigate the related factors influencing anxious‐depressive emotion of families of severe mental illness patients .Methods Assessments were carried out with the Self‐made General Fam‐ily Status Questionnaire ,Family Burden Scale of Disease (FBS) ,Self‐rating Anxiety Scale (SAS) and Self‐rating Depression Scale (SDS) among families of 265 severe mental illness patients .Results The families had significantly higher total scores on the SAS and SDS compared with Chinese norm (P<0 .01) . Patients’ pre‐and post‐illness family economy status ,per capita income/year and reimbursement propor‐tion of treatment costs were negatively related to severity of families’ depression and SAS total score nota‐bly (P<0 .05 or 0 .01) .Patients’ course and hospitalization times were positively related to severity of families’ depression and SAS total score notably (P<0 .01);Families’ education years were negatively re‐lated to their SAS total scores notably (P<0 .01) ,instability of patients’ condition and treatment costs/year were positively related to families’ SAS total scores notably (P<0 .05 or 0 .01) .The FBS total and each dimension score were positively related to severity of families’ depression and SAS total score notably (P<0 .01) .Conclusion Families of severe mental illness patients have obvious anxiety‐depression emo‐tional problem ,family burden of disease ,especially economic burden ,is the main factor influencing fami‐lies’ anxious‐depressive emotion .