干扰素(IFN)具有多种生物活性,不仅对病毒,而且对肿瘤都有抑制增殖的效果.1970年以来,对于实验性肿瘤的相继研究阐明了各种作用机制,例如对肿瘤细胞的直接作用,通过免疫系统发挥作用,促进巨噬细胞的吞噬功能对肿瘤病毒的抑制作用等.但目前由于供应不足,其抗肿瘤的效果,无论在基础研究方面还是在临床研究方面,都没能得到确切的评价.而对脑肿瘤的效果,几乎是未知的.作者采用了单独投与干扰素的方法,把6例恶性脑肿瘤患者分为大剂量投药组(300万u/隔日一次)和小剂量投药组(5万u/每周一次),治疗4个月以上的观察结果报告如下:全部病例于投药后全身状态改善.免疫指标PHA(植物血凝素)及PPD(结核菌素)皮内反应 Interferon (IFN) has a variety of biological activities, not only for the virus, but also has an inhibitory effect on proliferation of tumors. Since 1970, successive studies on experimental tumors have elucidated various mechanisms of action, such as direct effects on tumor cells. , Through the immune system to play a role in promoting the phagocytosis of macrophages on the inhibition of tumor virus and so on. However, due to lack of supply, its anti-tumor effect, both in basic research and in clinical research, have not been able to get exact The evaluation of brain tumors is almost unknown. The authors used a method of administering interferon alone. Six patients with malignant brain tumors were divided into large-dose groups (3 million U / once every other day) and small-dose administration. Group (50 000 u/once per week), the observation results of treatment for more than 4 months were reported as follows: All cases improved after systemic administration. Immune parameters PHA (phytohaemagglutinin) and PPD (piperculin) intradermal reaction