目的探究肝肿瘤介入治疗中运用微球后取得的临床成效。方法选取实验大鼠120例,并对所有实验大鼠建立相应的模型,选择其中身体状态较好的大鼠100例,并根据对小鼠肝动脉灌入药物的不同将其分为空白对照组、去甲斑蝥素组、去甲斑蝥素碘油组、空白微球组及去甲斑蝥素聚酸酐微球组,总共5个组,且每组分别为20个大鼠。针对肝肿瘤生长率、肝肿瘤细胞凋亡率、大鼠平均生存时间情况,对五组大鼠进行对比分析。结果在肝肿瘤生长方面,空白对照组生长率明显高于其他各组,P<0.05;针对肝肿瘤细胞凋亡情况,空白对照组凋亡率明显低于其他各组,P<0.05;在平均生存时间方面,空白对照组平均生存时间明显低于其他各组,P<0.05。结论肝肿瘤介入治疗中运用微球后取得的临床成效显著,在提高肝肿瘤细胞凋亡率和大鼠生长时间的同时,使肝肿瘤生长率明显降低,应在临床大力推广应用。 Objective To investigate the clinical effect of microspheres in the interventional treatment of liver tumors. Methods A total of 120 experimental rats were selected and all the rats were selected. One hundred rats with good physical condition were selected and divided into blank control group , Norcantharidin, norcantharidin lipiodol, blank microsphere group and norcantharidin polycarboxylic anhydride microsphere group, a total of five groups, and each group was 20 rats. According to the growth rate of liver tumors, the rate of apoptosis of liver tumor cells and the average survival time of rats, comparative analysis was made on the five groups of rats. Results In the growth of liver tumors, the growth rate of the blank control group was significantly higher than that of other groups (P <0.05). The apoptotic rate of the control group was significantly lower than that of the other groups (P <0.05) Survival time, the average survival time of the blank control group was significantly lower than the other groups, P <0.05. Conclusion The clinical effect of microspheres after interventional treatment of hepatic tumor is remarkable. While increasing the rate of hepatocarcinoma cell apoptosis and the growth of rat, the growth rate of hepatic tumor is obviously reduced, which should be promoted and applied clinically.