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目的探讨血液净化技术在ICU急性肾衰竭患者治疗中治疗模式的选择及疗效和并发症。方法回顾性分析急性肾衰竭患者行间歇性血液透析(IHD)和连续性肾脏替代治疗(CRRT),观察两种不同治疗方法的疗效,记录不良反应。结果 39例急性肾衰竭患者中,接受IHD治疗者13例,接受CRRT治疗者26例,其中26例患者经CRRT治疗,死亡13例,死亡率为50.0%,13例患者经IHD治疗,死亡7例,死亡率为53.8%,2组患者死亡率比较差异无统计学意义。IHD组并发症发生率为60.5%,CRRT组中并发症发生率为31.6%。结论 CRRT组和IHD组治疗的存活率差异无统计学意义,但CRRT血流动力学稳定,可使血液中血清肌酐、血尿素氮和血钾平稳下降,波动较小并可维持在较低水平,因此更加适用于ICU急性肾功能衰竭(ARF)患者。
Objective To investigate the choice of curative effect and complications of blood purification in the treatment of ICU patients with acute renal failure. Methods The patients with acute renal failure were retrospectively analyzed for intermittent hemodialysis (IHD) and continuous renal replacement therapy (CRRT). The curative effects of two different treatments were observed and the adverse reactions recorded. Results Of 39 patients with acute renal failure, 13 received IHD and 26 received CRRT. Of 26 patients, 13 died of CRRT, with a mortality rate of 50.0%. 13 patients were treated with IHD and died of 7 For example, the mortality rate was 53.8%. There was no significant difference in mortality between the two groups. The complication rate in IHD group was 60.5%, and the complication rate in CRRT group was 31.6%. Conclusion There was no significant difference in the survival rate between CRRT group and IHD group. However, hemodynamics of CRRT was stable, serum creatinine, blood urea nitrogen and serum potassium decreased steadily, with little fluctuation and remained at a low level , So it is more suitable for ICU patients with acute renal failure (ARF).