反流性食管病（GERD）是由于食管下段括约肌门。ES）抗反流屏障失调，酸性胃内容物反流并滞留食管，食管清除能力及食管粘膜防御能力下降等引起的食管慢性炎症。由于常有不典型病例，确切发病率难于统计。美国统计约为4％～10％［‘j。近年上海统计，根据症状本病患病率可达7％ Reflux esophageal disease (GERD) is due to lower esophageal sphincter gate. ES) anti-reflux barrier disorders, reflux of acidic gastric contents and retention of the esophagus, esophageal clearance and esophageal mucosal defense ability caused by chronic inflammation of the esophagus. As often atypical cases, the exact incidence is difficult to statistics. U.S. statistics are about 4% to 10% [’j. Shanghai statistics in recent years, according to the prevalence of the disease up to 7%