输血 ,这一在临床实践中应用广泛的治疗手段 ,已被认为是影响肿瘤患者预后的重要因素。这种影响被归诸于输血对机体免疫功能的调节———免疫抑制。有关输血对肿瘤患者预后影响的回顾性临床研究已相继开展 ;动物实验也在分子生物学水平取得了输血与免疫抑制机制研究的新突破。在积极开展针对性的前瞻性研究的同时 ,严格输血指征 ,提倡自体输血或成分输血 ,以减少输血对肺癌及其它肿瘤患者预后的不良影响 Blood transfusion, a widely used treatment in clinical practice, has been considered as an important factor affecting the prognosis of cancer patients. This effect is due to the regulation of immune function of the blood transfusion --- immunosuppression. Retrospective clinical studies on the impact of blood transfusion on the prognosis of cancer patients have been carried out one after another. Animal experiments have also made new breakthroughs in the research on the mechanisms of blood transfusion and immunosuppression at the molecular biology level. While proactively conducting targeted prospective studies, strict indications for blood transfusions are advocated to facilitate autologous blood transfusion or component transfusion to reduce the adverse effects of blood transfusions on the prognosis of patients with lung cancer and other cancers