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目的:探讨易化经皮冠状动脉腔内成形术(PCI)治疗对急性心肌梗死患者血浆脑钠肽水平和左心室重构的影响。方法:选择急性心肌梗死患者212例,其中易化PCI组116例,直接PCI组96例。所有患者分别于入院即刻、24 h、48 h、7 d、14 d及28 d时测定血浆脑钠肽水平;入院后24 h、28 d超声心动图测量左心室舒张末期容积指数、左心室收缩末期容积指数和左心室射血分数。结果:与直接PCI治疗组相比,易化PCI组血浆脑钠肽水平明显降低,左心室射血分数明显升高,左心室客积下降。结论:易化PCI可明显降低血浆脑钠尿肽水平并减轻左心室重构。
Objective: To investigate the effect of percutaneous transluminal coronary angioplasty (PCI) on plasma brain natriuretic peptide and left ventricular remodeling in patients with acute myocardial infarction. Methods: A total of 212 patients with acute myocardial infarction were selected, including 116 patients in the facilitated PCI group and 96 in the direct PCI group. Plasma BNP levels in all patients were measured immediately after admission, 24 h, 48 h, 7 d, 14 d and 28 d respectively. The left ventricular end-diastolic volume index and left ventricular systolic volume were measured by echocardiography at 24 h and 28 d after admission Terminal volume index and left ventricular ejection fraction. Results: Compared with the direct PCI group, the plasma BNP level in the Yi-Hua PCI group was significantly lower, the left ventricular ejection fraction was significantly higher and the left ventricular mass was decreased. Conclusions: Yi-li PCI can significantly decrease plasma BNP level and relieve left ventricular remodeling.