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辅酶 Q_(10)(CoQ_(10))产生于人细胞线粒体内,是与能量转换有关的几个酶系的辅因子。心肌细胞内线粒体CoQ_(10)的含量极为丰富,CoQ_(10)缺乏时将对心肌功能产生重要的影响。作者自1982年11月起选择扩张型心肌病作长期的研究,旨在确定 CoQ_(10)长期治疗的耐受性及其临床改善的持久性。
Coenzyme Q_ (10) (CoQ_ (10)) is produced in mitochondria of human cells and is a cofactor of several enzyme systems involved in energy conversion. Myocardial cells mitochondrial CoQ_ (10) content is extremely rich, CoQ_ (10) lack of myocardial function will have a significant impact. The author has been conducting a long-term study of dilated cardiomyopathy since November 1982 to determine the tolerability of long-term treatment of CoQ_ (10) and the persistence of its clinical improvement.