近年来 ,随着医药工业的发展 ,新药大量涌现 ,由药物引起的疾病日趋增多。肝脏是药物浓集、转化、代谢的主要器官 ,又是机体免疫的重要脏器。因此 ,药物性肝病更为多见。据报道药物性肝病占药物不良反应的 10 %～ 15 % ,药物性肝病患者均有原发疾病 ,肝损害症状常被原发病所掩 In recent years, with the development of the pharmaceutical industry, a large number of new drugs have emerged and the number of diseases caused by drugs has been on the increase. Liver is the main organ of drug concentration, transformation and metabolism, and is also an important organ of the body immunity. Therefore, drug-induced liver disease is more common. It is reported that drug-induced liver disease accounted for 10% of adverse drug reactions 15%, patients with drug-induced liver disease have primary disease, liver damage symptoms are often covered by the original disease