论文部分内容阅读
目的探讨乳腺浸润性导管癌超声征象与病理组织学分级及ER、PR表达的相关性。方法44例乳腺癌均经病理组织学证实,且所有病例在治疗前均行乳腺超声检查,术后进行病理组织学分级及测定ER、PR的表达。分析乳腺癌的超声表现与病理组织学分级及ER、PR表达的相关性。结果浸润性导管癌的组织学分级与肿块大小二者之间呈正相关变化趋势;超声征象与病理组织学分级之间无明显相关性;组织学分级与血流分级呈正相关变化趋势。毛刺征组、周边强回声晕组、后方回声衰减组ER、PR表达的阳性率较无毛刺组、无周边强回声晕组、无后方回声衰减组高;ER、PR的表达与血流丰富程度无明显相关性;随着肿块体积的增大,ER、PR表达的阳性率越低。结论乳腺浸润性导管癌超声征象与病理组织学分级及ER、PR的表达密切相关,对病理组织学分级有提示作用,且在一定程度上反映了ER、PR的表达状态。
Objective To investigate the correlation between ultrasonographic features and histopathological grading of breast invasive ductal carcinoma and expression of ER and PR. Methods Totally 44 cases of breast cancer were confirmed by histopathology. All cases underwent ultrasound examination before operation. The pathological grade and the expression of ER and PR were measured after operation. Analysis of breast ultrasound findings and histopathological grading and ER, PR expression correlation. Results There was a positive correlation between histological grade and size of tumor in invasive ductal carcinoma. There was no significant correlation between ultrasound signs and histopathological grade. The histological grade and the grade of blood flow showed a positive correlation. The positive rates of ER and PR in the echogenic group and the peripheral echogenic group were significantly higher than those in the non-glitched group, the peripheral echogenic group and the non-posterior echogenic group. The expression of ER, PR and the abundance of blood flow No significant correlation; as the volume of the tumor increases, the lower the positive rate of ER and PR expression. Conclusion The echocardiographic features of invasive ductal carcinoma of the breast are closely related to the histopathological grade and the expression of ER and PR, which may be indicative of histopathological grade, and to a certain extent reflect the expression of ER and PR.