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急性丙烯酸甲酯吸入毒性研究表明,大鼠、小鼠和家兔LC_(50)分别为6400、8800和6800mg/m~3。对人的嗅阈为1.5mg/m~3,刺激阈浓度为31mg/m~3。慢性阈浓度为100mg/m~3。对大鼠有胚胎毒性。Ames试验阳性。工人接触丙烯酸甲酯平均浓度为21.3mg/m~3,出现神经衰弱和刺激作用的症状、体征。建议丙烯酸甲酯的最高容许浓度为15mg/m~3。经劳动卫生标准分委员会审议通过为20mg/m~3。
Inhalation toxicity of acute methyl acrylate showed that the LC 50 of rats, mice and rabbits were 6400, 8800 and 6800 mg / m ~ 3, respectively. Odor threshold for people 1.5mg / m ~ 3, stimulus threshold concentration of 31mg / m ~ 3. Chronic threshold concentration of 100mg / m ~ 3. Rat embryotoxicity. Ames test positive. Workers exposed to methyl acrylate average concentration of 21.3mg / m ~ 3, neurasthenia and irritation of the symptoms and signs. The recommended maximum concentration of methyl acrylate is 15mg / m ~ 3. The labor and health standards sub-committee examined and adopted as 20mg / m ~ 3.