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目的了解妊娠高血压综合征(简称妊高征)胎儿-胎盘循环规律。方法对临床诊断中、重度妊高征患者(妊高征组)采用彩色多普勒超声在脐带不同位点(胎盘附着部、漂浮部、脐轮部)、胎盘后方螺旋动脉测量血流参数,并与对照组比较。结果对照组脐带不同位点的脐血流自胎盘附着部至脐轮部为由低至高的血流趋势,而妊高征组孕29～40周脐带不同位点脐血流也呈由低至高的血流趋势,但较对照组高,统计学检验差异不明显。而孕29～40周胎盘后方螺旋动脉搏动指数(PI)、阻力指数(RI)、脐血流收缩期与舒张期比值(S/D)与对照组比较有显著性差异(P<0.05)。对照组与妊高征组出生体重有明显差异。结论异常组胎盘后方螺旋动脉血流阻力增高,导致脐血流增高,进而影响胎儿发育。
Objective To understand the pregnancy-induced hypertension syndrome (PIH) fetal-placental circulation. Methods In clinical diagnosis, patients with severe PIH (PIH group) underwent color Doppler ultrasound to measure blood flow parameters at different sites of umbilical cord (placenta, flotation and navel) And compared with the control group. Results In the control group, umbilical blood flow at different sites of umbilical cord from the placenta attached to the umbilical part of the blood flow from low to high trends, and pregnancy induced hypertension group 29 to 40 weeks umbilical cord cord umbilical cord blood flow at different sites also from low to high Of the blood flow trend, but higher than the control group, the statistical test was not obvious. Compared with the control group, there was a significant difference (P <0.05) in the posterior spiral artery pulsatility index (PI), resistance index (RI), umbilical blood flow systolic and diastolic ratio (S / D) There were significant differences in birth weight between control group and PIH group. Conclusion Abnormal group of placenta posterior spiral artery blood flow resistance increased, leading to increased umbilical cord blood flow, and thus affect fetal development.