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目的比较单纯支气管扩张和支气管扩张合并支气管哮喘患者呼出气一氧化氮(FENO)水平的差异。方法96例胸部CT诊断的支气管扩张患者进行肺功能和气道反应测定后分单纯支气管扩张组和支气管扩张合并支气管哮喘组,运用纳库仑一氧化氮分析仪测定两组患者FENO水平。结果 96例支气管扩张患者中30例(31.25%)提示气道高反应性,显示合并支气管哮喘,该组FENO水平(67.59±31.83)明显高于单纯支气管扩张组(23.95±13.11),差异有统计学意义(P<0.05)。结论 FENO可用于鉴别支气管扩张中合并支气管哮喘患者,可应用来指导治疗。
Objective To compare the differences of exhaled nitric oxide (FENO) levels between patients with bronchiectasis and bronchiectasis alone and with bronchial asthma. Methods Ninety-six patients with bronchiectasis diagnosed by chest CT were divided into simple bronchiectasis group and bronchiectasis bronchial asthma group after lung function and airway reaction were measured, and the levels of FENO in both groups were determined by using the analyzer of Nocouple NO. Results Thirty patients (31.25%) in 96 patients with bronchiectasis presented with airway hyperresponsiveness and showed bronchial asthma. The FENO level in the group of 96 bronchiolitis was significantly higher than that in the group of simple bronchiectasis (23.95 ± 13.11) Significance (P <0.05). Conclusion FENO can be used to identify bronchiectasis in patients with bronchial asthma, can be used to guide the treatment.