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目的:了解我院老年精神病患者用药状况及特点。方法:统计分析2010年7月16日我院>60岁老年住院精神病患者全部用药记录,比较精神疾病伴躯体疾病与不伴躯体疾病患者抗精神病药物使用剂量的差异性,用限定日剂量(DDD)、药物利用指数(DUI)为指标,分析用药剂量合理性。结果:非经典抗精神病药物仍占主导位置:奥氮平100例(30.3%)占第一位;伴躯体疾病与不伴躯体疾病的老年精神患者奥氮平、喹硫平、利培酮、氯氮平、氯丙嗪等药物的平均日剂量差异无统计学意义(P>0.05),DUI均<1。抗精神病药物以单一应用为主。结论:精神疾病伴躯体疾病与不伴躯体疾病老年患者抗精神病药物使用剂量无明显差异,精神药物使用基本合理。
Objective: To understand the use of drugs and characteristics of elderly patients with mental illness in our hospital. Methods: Statistical analysis was conducted on all medication records of 60-year-old hospitalized patients with psychosis in our hospital on July 16, 2010. The differences in the dosage of antipsychotic drugs among mental illness and somatic diseases were compared. The daily dose (DDD ), Drug utilization index (DUI) as an indicator, the rationale of the dosage was analyzed. Results: Non-classical antipsychotics still dominated: 100 cases (30.3%) of olanzapine took the first place; olanzapine, quetiapine, risperidone, The average daily dose of clozapine, chlorpromazine and other drugs had no significant difference (P> 0.05), DUI was <1. Antipsychotics are dominated by a single application. Conclusion: There is no significant difference in the dosage of antipsychotic drugs in the elderly patients with mental illness and somatic diseases, and the use of psychotropic drugs is reasonable.