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目的探讨出生缺陷风险评分数学模型的建立,为出生缺陷防治提供依据。方法对我市近5年来有生育(包括死胎、死产、活产)的家庭入户进行问卷调查,通过问卷调查、体格检查,对粤北山区市连州市出生缺陷相关风险因素进行分析,并采用Logistic回归模型分析相关影响因素。结果共调查了31 548名新生儿,共检出有出生缺陷的新生儿683名(216/万人),共筛选出20种主要风险因素。结论根据各风险因素的风险值建立出生缺陷风险评分数学模型,实用、简单。对出生缺陷的防治有一定作用。
Objective To explore the establishment of a mathematic model of birth defects risk score to provide evidence for the prevention and treatment of birth defects. Methods A questionnaire survey was carried out on the household households with fertility (including stillbirth, stillbirth and live birth) in the past five years in our city. Through questionnaire and physical examination, the risk factors related to birth defects in Lianzhou city of northern Guangdong were analyzed. Logistic regression model was used to analyze the related factors. Results A total of 31 548 newborns were investigated. A total of 683 newborns (2.16 million) with birth defects were screened and 20 major risk factors were screened out. Conclusion According to the risk factors of risk factors, a mathematical model of birth defects risk score is established, which is practical and simple. Prevention of birth defects have a role.