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随着糖尿病患病率的逐年增加,降糖药物的使用越来越广泛,其不良反应也在迅速增加。其中,由于水钠潴留导致心力衰竭的风险增加,因此降糖药物治疗与水钠潴留相关性近年来受到重视。引起水钠潴留的降糖药物主要包括噻唑烷二酮类(TZDs)和胰岛素。在临床工作中如何科学选择和应用这些药物,确保患者的安全,已成为糖尿病治疗中的主要问题之一。
With the increasing prevalence of diabetes, the use of hypoglycemic drugs is more and more widespread, and its adverse reactions are also rapidly increasing. Among them, due to water and sodium retention leading to an increased risk of heart failure, hypoglycemic drug treatment and Shuinazhuli correlation has been paid attention in recent years. Hypoglycemic agents that cause sodium and water retention include mainly thiazolidinediones (TZDs) and insulin. How to select and apply these drugs scientifically in clinical work to ensure the safety of patients has become one of the major problems in the treatment of diabetes.