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为了探讨溃疡性结肠炎的发病机制和治疗机理,我们用免疫法制成大鼠溃疡性结肠炎实验模型,并用中药溃结康胶囊进行复健治疗,现将研究结果报告如下。材料和方法1 动物系河北医科大学实验动物中心提供的 Wistar 雄性大白鼠,共60只,体重150～180g。实验期间喂以定量配方饲料,自由饮水。2 药物溃结康胶囊(简称溃结康,由河北省中医药研究院制剂室提供,内含黄精、灵芝、忍冬藤、青黛、徐长卿、白花蛇舌草等,每10粒含生药5g)研细粉,用蒸馏水配制成浓度为15%、7.5%的混悬液。补脾益肠丸(广州陈李济药厂生产,每1内杯
In order to investigate the pathogenesis and therapeutic mechanism of ulcerative colitis, we established an experimental model of ulcerative colitis in rats by immunotherapy and reconstituted with Kuijiekang capsule. The results of this study are reported below. Materials and Methods 1 Animals Wistar male rats provided by Experimental Animal Center of Hebei Medical University, a total of 60, weighing 150-180g. Quantitative formula feed was fed during the experiment to allow free drinking. 2 Drug Kuijiekang Capsule (abbreviated as Kuijiekang, provided by the preparation room of the Hebei Provincial Academy of Traditional Chinese Medicine, containing Huangjing, Ganoderma lucidum, Lonicera japonica, barley, Xuchangqing, Hedyotis diffusa, etc., containing 5g of crude drug per 10 capsules) Fine powder, formulated with distilled water to a 15%, 7.5% suspension. Bupi Yichang Pills (Guangzhou Chen Liji Pharmaceutical Factory, 1 cup each