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在Prinzmetal变异型心绞痛中,已经证实了冠状动脉痉挛与心肌缺血的关系。冠状动脉的自发性痉挛既可发生在变异型心绞痛和造影正常的患者,亦可发生在有明显血管阻塞的患者中。有些在休息时发生心绞痛和缺血性S—T段压低的患者,冠状动脉造影未能显示血管有阻塞;因此,冠状动脉痉挛亦可能是这些患者出现休息时心绞痛的原因。一般认为,急性心肌梗塞与冠状动脉血栓形成或斑块出血有关,而冠状动脉痉挛可促使血栓形成或造成斑块出血,反之斑块出血或血栓形成又可导致冠状动脉痉挛。Prinzmetal最初报道的32例变
In Prinzmetal variant angina, the relationship between coronary spasm and myocardial ischemia has been demonstrated. Spontaneous spasm of the coronary artery may occur in patients with variant angina and normal imaging, but also in patients with significant vascular obstruction. In patients with angina pectoris and ischemic S-T depression at rest, coronary angiography fails to show blockage of the blood vessels; therefore, coronary artery spasm may also be responsible for angina at rest in these patients. Is generally believed that acute myocardial infarction and coronary thrombosis or plaque bleeding, and coronary artery spasm can promote thrombosis or plaque bleeding, whereas plaque bleeding or thrombosis can lead to coronary artery spasm. Prinzmetal initially reported 32 cases changed