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目的探讨血尿酸(SUA)水平与2型糖尿病(T2DM)血管病变的关系。方法 64例T2DM患者,根据SUA水平分为高SUA水平组(HUA组,34例)与正常SUA水平组(NUA组,30例),比较两组血管病变发生率。结果 HUA组SUA、甘油三酯(TG)、肌酐(Cr)及尿微量白蛋白(m Alb)高于NUA组(P<0.05);HUA组糖尿病肾病、脑血管病及冠心病发生率(67.65%、44.12%、61.76%)高于NUA组(P<0.05);SUA与血糖(FBG)、尿素氮(BUN)、Cr、m Alb及TG相关(P<0.05)。结论 SUA水平的升高与T2DM患者血管病变的发生具有相关性。
Objective To investigate the relationship between serum uric acid (SUA) and type 2 diabetes mellitus (T2DM). Methods Sixty - four T2DM patients were divided into high SUA group (34 cases) and normal SUA group (30 cases) according to SUA level. The incidence of vascular lesions in both groups were compared. Results The levels of SUA, TG, creatinine and m Alb in HUA group were higher than those in NUA group (P <0.05). The incidence of diabetic nephropathy, cerebrovascular disease and coronary heart disease in HUA group (67.65 %, 44.12% and 61.76% respectively) were higher than those in NUA group (P <0.05). SUA was correlated with FBG, BUN, Cr, m Alb and TG (P <0.05). Conclusions The elevation of SUA is correlated with the occurrence of vascular lesions in T2DM patients.