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目的探讨降低儿童乙型肝炎病毒(HBV)携带率的方法以及对策发挥的疗效作用。方法对2010年～2012年4月入住我院就诊的120例产妇及其所生婴儿进行乙型肝炎检测,检测产妇血和婴儿脐带血中的HBVDNA含量。将120例患者分为肝炎病毒感染的实验组和无肝炎病毒感染的对照组,观察两组患者在住院期间的各种临床资料和他们的肝炎病毒治疗效果。结果 120例患者中感染组所占比率低于无感染组,感染组有42例占35%,无感染有78例占65%。产妇血的HBV与婴儿的血液HBV含量呈正相关。两组婴儿的体重和性别以及产妇血、脐带血对照值为(P>0.05),无统计学差异。结论新生儿携带乙型肝炎病毒大多来自产妇在妊娠期感染肝炎病毒所致,通过产妇血和婴儿脐带血的HBVDNA检测能够比较确切得出婴儿感染乙型肝炎病毒情况,但是产妇的年龄、体重以及自身选择生产的形式等方面均与婴儿的肝炎病毒感染无关。
Objective To explore ways to reduce the carrier rate of hepatitis B virus (HBV) in children and the curative effect of countermeasures. Methods A total of 120 pregnant women and their infants admitted to our hospital from 2010 to April 2012 were tested for hepatitis B virus (HBV), and HBVDNA content in maternal blood and infant cord blood was detected. 120 patients were divided into hepatitis B virus infection experimental group and control group without hepatitis virus infection. The clinical data of two groups of patients during hospitalization and the therapeutic effect of their hepatitis virus were observed. Results The proportion of infected patients in 120 patients was lower than that in non-infected patients. In infected patients, 42 patients accounted for 35% and 78 patients accounted for 65%. Maternal blood HBV and the baby’s blood HBV content was positively correlated. The weight and gender of the two groups of infants and maternal blood, cord blood control value (P> 0.05), no significant difference. Conclusions Most of the newborns with hepatitis B virus are from the hepatitis B virus infection during pregnancy. The detection of HBVDNA by maternal blood and cord blood of infants can accurately determine the infant’s infection with hepatitis B virus. However, the age, weight, Their own choice of production and other aspects of the baby’s hepatitis virus infection has nothing to do.