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Survivin是1997年耶鲁大学Altieri实验室利用EPR-1cDNA筛选人类基因组文库获得的IAP[1]。它是迄今为止已经鉴定的八个IAPs家族成员(X-IAP、c-IAP-1、c-IAP-2、NAIP、ILP-2、ML-IAP/Livin、apollon、survivin)中分子量(16·5kD)最小和最有基础与临床意义因而备受关注的明星分子[
Survivin is an IAP obtained from the 1997 Genome Library at Yale University using the EPR-1 cDNA in the Altieri Laboratory [1]. It is one of the eight IAPs family member (X-IAP, c-IAP-1, c-IAP-2, NAIP, ILP-2, ML-IAP / Livin, apollon, survivin) 5kD) Minimal and most basic and clinical significance of the stars and thus the concern [