汉防已甲素(tetrandrine,以下简称甲素)系汉防已(Stephania tetrandriaS.Moor)中主要生物碱之一,具有降压、镇痛、松弛横纹肌、抑制肿瘤生长等作用,临床上已用于高血压病、神经性疼痛以及肿瘤的实验性治疗。64年我组在离体兔心上观察到甲素能显著扩张冠状动脉增加其流量,同时又看到它对垂体后叶素性冠脉痉挛亦具有明显对抗作用。为了进一步探讨甲素在 Tetrandrine is one of the main alkaloids in Stephania tetrandria S. Moor. It has antihypertensive, analgesic, relaxing striated muscle, inhibits tumor growth, and has been used clinically. For the treatment of hypertension, neuropathic pain, and tumors. In the 64-year-old rabbit group, we observed that Alzheimer’s can significantly expand the coronary arteries and increase their flow. At the same time, it was also seen that it has a significant antagonistic effect on pituitary vasospasm. In order to further explore the