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目的观察评价中西医结合治疗早发型子痫前期(EOP)临床疗效与安全性。方法以2013年4月-2015年1月医院收治的EOP患者作为研究对象,共纳入患者122例,据入院顺序,采用随机队列插入法,将患者分为西医组、联合组各61例,均给予生活干预、硫酸镁等药物降压,对症治疗,联合组在此基础上给予中药处方治疗,对比临床疗效与相关指标水平。结果联合组痊愈率75.61%高于西医组,差异具有统计学意义(P<0.05);治疗后,联合组与西医组APPT高于治疗前、联合组高于西医组,联合组与西医组IR低于治疗前、联合组低于西医组,联合组FIB高于西医组,差异具有统计学意义(P<0.05);两组均未见严重不良反应;联合组新生儿疾病发生率低于西医组,差异具有统计学意义(P<0.05)。结论中西医结合治疗EOP疗效较好,有助于减轻患者症状表现,改善活产儿预后。
Objective To observe and evaluate the clinical efficacy and safety of integrated traditional Chinese and western medicine in the treatment of early-onset preeclampsia (EOP). Methods A total of 122 patients with EOP were enrolled in our hospital from April 2013 to January 2015. According to the sequence of admission, randomized cohort method was used to divide the patients into two groups: 61 cases in Western medicine group and 61 cases in combined group Give life intervention, magnesium sulfate and other drugs antihypertensive, symptomatic treatment, the combination group on this basis to give Chinese medicine prescription treatment, compared with clinical efficacy and related indicators. Results The cure rate in combined group was 75.61% higher than that in Western medicine group (P <0.05). After treatment, the APPT in combined group and western medicine group was higher than that before treatment, and the combined group was higher than Western medicine group Before treatment, the combined group was lower than the western medicine group, and the FIB in the combined group was higher than that in the western medicine group (P <0.05); no severe adverse reactions were found in both groups; the incidence of neonatal diseases in the combined group was lower than that in the Western medicine Group, the difference was statistically significant (P <0.05). Conclusion The combination of traditional Chinese and Western medicine treatment of EOP better effect, help to reduce the symptoms of patients and improve the prognosis of live births.