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目的:观察异位妊娠患者联合应用米非司酮、甲氨蝶呤治疗的临床效果。方法:选取2011年10月-2014年10月大理市第一人民医院收治的100例异位妊娠患者,按硬币法将其分成观察组和对照组,各50例。对照组应用甲氨蝶呤治疗,观察组在对照组治疗的基础上应用米非司酮治疗,对比异位妊娠治疗效果。结果:治疗后,观察组β人绒毛膜促性腺激素(β-HCG)水平为(682.32±302.31)IU/L,血清β-HCG转阴时间为(11.32±2.21)d,住院时间为(10.36±3.62)d,异位妊娠治疗总有效率为94.0%,患者不良反应发生率为10.0%,,组间比较,差异均具有统计学意义(P<0.05)。结论:米非司酮、甲氨蝶呤联合治疗异位妊娠,疗效确切,安全性高。
Objective: To observe the clinical effect of mifepristone and methotrexate combined with ectopic pregnancy. Methods: A total of 100 patients with ectopic pregnancy admitted to the First People’s Hospital of Dali from October 2011 to October 2014 were selected and divided into observation group and control group according to the coin method, 50 cases in each group. The control group was treated with methotrexate. The observation group was treated with mifepristone on the basis of the control group, comparing the therapeutic effect of ectopic pregnancy. Results: After treatment, the β-HCG level in the observation group was (682.32 ± 302.31) IU / L, the serum β-HCG negative conversion time was (11.32 ± 2.21) days and the hospitalization time was (10.36 ± 3.62) d, the total effective rate of ectopic pregnancy treatment was 94.0%, the incidence of adverse reactions in patients was 10.0%, the differences between the two groups were statistically significant (P <0.05). Conclusion: Mifepristone and methotrexate combined treatment of ectopic pregnancy, exact effect, high safety.