论文部分内容阅读
目的:探讨七氟醚应用于小儿眼科手术诱导和维持的安全性和可行性。方法:选择择期眼科手术的患儿60例,随机分为七氟醚组(A组)和氯胺酮组(B组)各30例。观察术中各时点的心率变化,摇头、肢体活动的发生情况;七氟醚吸入诱导睫毛反射消失和疼痛消失时间;观察术后清醒时间,记录术后躁动、恶心、呕吐及呼吸系统意外事件发生情况。结果:术中各时点心率A组较术前明显减慢,B组明显加快,两组间存在统计学差异(P<0.05);A组在诱导时有23例出现不自主运动,术中均未发现摇头、肢体活动;七氟醚吸入诱导睫毛反射消失和疼痛消失时间分别为(60±4)s和(106±11)s;术后清醒时间A组(12.0±0.6)min,B组(33.0±2.6)min,A组比B组明显缩短(P<0.05);A组术后未出现躁动、恶心呕吐及呼吸系统意外事件,而B组分别发生躁动8例,恶心呕吐3例,呼吸系统意外事件2例。结论:七氟醚吸入麻醉应用于小儿眼科手术是一种较为理想和安全的麻醉方法。
Objective: To investigate the safety and feasibility of sevoflurane in the induction and maintenance of pediatric ophthalmic surgery. Methods Sixty children with elective ophthalmic surgery were randomly divided into sevoflurane group (A group) and ketamine group (B group) with 30 cases each. The change of heart rate at each time point, shaking head and limb activity were observed. Sevoflurane inhalation induced the disappearance of lashes and disappearance of pain. The postoperative awake time was observed. The postoperative agitation, nausea, vomiting and respiratory accident were recorded What happened? Results: At each time point, the heart rate in group A was significantly lower than that in preoperative and group B was significantly increased (P <0.05). In group A, 23 patients developed involuntary movements during the operation, (60 ± 4) s and (106 ± 11) s, respectively. The awake time of group A (12.0 ± 0.6) min, group B Group A (33.0 ± 2.6) min, group A was significantly shorter than group B (P <0.05); Group A had no restlessness, nausea and vomiting and respiratory accident, while group B had restlessness in 8 cases and nausea and vomiting in 3 cases , 2 cases of respiratory accident. Conclusion: Sevoflurane inhalation anesthesia is an ideal and safe anesthetic method for pediatric ophthalmic surgery.