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目的分析受血者发生不良反应的原因,为临床降低输血不良反应提供参考。方法对医院住院58例患者输血发生不良反应的原因进行分析。结果 2007年1月-2015年12月间输血患者8423例,发生输血不良反应56例,其中过敏反应41例(73.2%),发热反应11例(19.6%),其他反应例4(7.1%),总不良反应发生率为0.66%;输注冰冻血浆、去白悬浮红细胞、血小板和冷沉淀的输血反应所占比例分别为83.9%、12.5%、1.8%和1.8%;有输血史/妊娠史者非感染性输血不良反应发生率高于无输血史/妊娠史者(P<0.05)。结论发生的输血不良主要为过敏反应和发热反应,且以血浆成分输血导致的不良反应为主,其他成分较低,对于有输血史/妊娠史患者应加强监控及观察,减少不良反应发生。
Objective To analyze the causes of adverse reactions in recipients and provide reference for reducing the adverse reactions in transfusion. Methods The causes of adverse reactions of blood transfusion in 58 hospitalized patients were analyzed. Results A total of 8423 patients were transfused from January 2007 to December 2015 with 56 cases of transfusion adverse reactions, including 41 cases (73.2%) of allergic reactions, 11 cases (19.6%) of fever reactions and 4 cases (7.1%) of other reaction cases. , The total incidence of adverse reactions was 0.66%; the percentage of transfusion reaction of transfusion of frozen plasma, white-suspended erythrocytes, platelets and cryoprecipitate were 83.9%, 12.5%, 1.8% and 1.8% respectively; The incidence of noninfectious transfusion adverse reactions was higher than that without transfusion history or pregnancy (P <0.05). Conclusions The main causes of blood transfusion are anaphylaxis and fever, and the adverse reactions caused by transfusion of plasma components are the main components. The other components are low. Patients with history of blood transfusion / pregnancy should be monitored and observed to reduce adverse reactions.