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目的观察中药养阴活血方防治鼻咽癌放疗致口咽放射损伤的疗效。方法将156例鼻咽癌住院患者随机分为A组(78例)、B组(78例),两组均接受相同条件的放射治疗,但A组放射治疗同时配合用自拟中药养阴活血方1号合剂治疗,B组是常规放射治疗。观察放疗后口咽黏膜放射反应的情况。结果放疗后两组的口咽黏膜急性放射反应总的发生率基本相似,但A组的程度比B组轻,Ⅰ、Ⅱ级比较差异有显著意义(P<0.05);口咽黏膜放射反应的初发时间,两组比较差异有显著意义(P<0.05)。结论中药养阴活血合剂对放射性黏膜损伤有明显的防治作用。
Objective To observe the curative effect of traditional Chinese medicine Yangyin Huoxue Fang in preventing and treating nasopharyngeal carcinoma radiation-induced oropharyngeal radiation injury. Methods A total of 156 inpatients with nasopharyngeal carcinoma were randomly divided into group A (78 cases) and group B (78 cases). Both groups received radiation therapy under the same conditions. However, group A radiation therapy combined with self-made traditional Chinese medicine Yangyin Huoxue Fang 1 mixture treatment, B group is a conventional radiation therapy. Observe the radiation response of oropharyngeal mucosa after radiotherapy. Results The total incidence of acute oropharyngeal mucosal acute radiation reaction in both groups was similar after radiotherapy, but the degree of A group was lighter than that of B group, and there was significant difference between Ⅰ and Ⅱ (P <0.05). The radiation response of oropharyngeal mucosa The initial time, the difference between the two groups was significant (P <0.05). Conclusion Traditional Chinese Medicine Yangyin Huoxue Mixture has obvious preventive and therapeutic effects on radioactive mucosal injury.