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目的探讨连续肾脏替代疗法(CRRT)治疗重症横纹肌溶解综合征(RM)并急性肾衰竭的临床效果。方法选取重钢总医院2014年4月—2016年4月收治的重症RM并急性肾衰竭患者30例,患者均采用CRRT治疗,随访1年,记录比较患者透析前后尿素氮、血肌酐、电解质变化情况。结果透析后6~11 d,患者进入多尿期;透析后10~19 d,患者各项指标明显好转。患者透析后尿素氮、血肌酐水平低于透析前,K+、P+离子浓度低于透析前,Ca2+浓度高于透析前(P<0.05)。结论采用CRRT治疗重症RM并急性肾衰竭的临床效果显著,可有效纠正电解质失衡,有助于改善患者预后。
Objective To investigate the clinical effect of continuous renal replacement therapy (CRRT) in the treatment of severe rhabdomyolysis syndrome (RM) and acute renal failure. Methods Thirty patients with severe RM and acute renal failure who were treated in ChongQing General Hospital from April 2014 to April 2016 were selected. The patients were treated with CRRT for one year. The changes of blood urea nitrogen, serum creatinine and electrolyte before and after dialysis were recorded Happening. Results After 6 ~ 11 days after dialysis, the patients entered the polyuria stage. After the dialysis 10 ~ 19 days, the indexes of the patients improved obviously. Patients with dialysis after the urea nitrogen, serum creatinine levels before dialysis, K +, P + ion concentration was lower than before dialysis, Ca2 + concentration was higher than before dialysis (P <0.05). Conclusion The clinical effect of CRRT on severe RM and acute renal failure is significant, which can effectively correct electrolyte imbalance and improve prognosis.