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目的观察西格列汀联合二甲双胍治疗2型糖尿病的临床效果。方法选取该院2014年5月-2015年5月收治的2型糖尿病患者50例,采取随机数字表法将患者分为试验组和对照组各25例,对照组给予二甲双胍治疗,试验组在此基础上联合西格列汀治疗,对2组患者治疗13周后的糖化血红蛋白、餐后2h血糖及空腹血糖水平进行检测。结果试验组患者的糖化血红蛋白、空腹血糖及餐后2h血糖水平均明显低于对照组,差异均有统计学意义(P<0.05)。结论在治疗2型糖尿病时,应用西格列汀联合二甲双胍治疗患者的血糖有明显改善,提高了患者的满意度,在临床中应用和推广具有重要意义。
Objective To observe the clinical effect of sitagliptin and metformin in the treatment of type 2 diabetes mellitus. Methods Fifty patients with type 2 diabetes mellitus were selected from May 2014 to May 2015 in our hospital. Patients were divided into experimental group and control group (n = 25) by random number table. The control group was treated with metformin Based on the combination of sitagliptin treatment, the two groups of patients after 13 weeks of treatment of glycosylated hemoglobin, 2h postprandial blood glucose and fasting plasma glucose levels were detected. Results The levels of HbA1c, fasting blood glucose and postprandial 2h blood glucose in the experimental group were significantly lower than those in the control group (P <0.05). Conclusion In the treatment of type 2 diabetes, the application of sitagliptin and metformin in patients with significant improvement in blood glucose, improve patient satisfaction, clinical application and promotion of great significance.