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据估计当前在全世界已有150多万妇女应用醋酸甲孕酮(DMPA)及庚酸炔诺酮(NET-OEN)作为避孕药。并发现阴道出血紊乱是造成停药的主要原因,本文对继续用药和中断用药者的出血类型作详细的对比,以确定那些异常出血是引起妇女停药的原因。材料和方法:在10个中心进行了庚酸炔诺酮和醋酸甲孕酮的对比临床试验。本研究用单一方案和标准记录格式,以便呈送世界卫生组织作资料处理。庚酸炔诺酮是1ml油剂含药200mg,醋酸甲孕酮是结晶混悬水剂每ml含药150mg,两种药都是每隔12周±5天肌注一次。将受试者随机使用庚酸炔诺酮或用醋酸甲孕酮。对再次注射的就诊者,
It is estimated that more than 1.5 million women worldwide now use DMPA and NET-OEN as contraceptives. And found that vaginal bleeding disorder is the main reason for discontinuation of this article continued to use drugs and interrupt the type of bleeding were compared in detail to determine those who cause abnormal bleeding is the cause of withdrawal of women. Materials and Methods: A comparative clinical trial of norethindrone enolate and medroxyprogesterone acetate was conducted in 10 centers. This study uses a single protocol and standard record formats for submission to WHO for data processing. Norethisterone enoate is 1ml oil medicine containing 200mg, medroxyprogesterone acetate crystal suspension medicine per ml containing 150mg, two drugs are intramuscularly ± 5 days every 12 weeks once. Subjects were randomized to norethindrone heptanoate or medroxyprogesterone acetate. For re-injection of the doctor,