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目的观察乳果糖对老年便秘的疗效。方法158例老年便秘口服乳果糖溶液15~30ml/d,清洗1周,服药2周,停药1周继续观察排便次数,粪便性状等。结果(1)凡口服乳果糖溶液15~30ml/d,24小时起始通便者占61%,48小时通便占28%,72小时通便占8.2%。(χ2=5.991,P<0.05)。(2)显效60.1%,有效33.6%,无效6.3%。(3)出现腹痛不适不良反应为10.1%。调整剂量后消失。结论老年便秘口服乳果糖溶液起始剂量以15~30ml/d为宜。现以排便次数增加3次/天以上,粪质变软、量多者为总有效,则总有效率为93.7%。
Objective To observe the effect of lactulose on senile constipation. Methods 158 senile constipation oral lactulose solution 15 ~ 30ml / d, cleaning for 1 week, taking 2 weeks, stopping for 1 week to observe the number of defecation, stool characteristics. Results (1) All oral lactulose solution 15 ~ 30ml / d, the first 24 hours of laxatives accounted for 61%, 48 hours of catharsis accounted for 28%, 72 hours of catharsis accounted for 8.2%. (Χ2 = 5.991, P <0.05). (2) Effective 60.1%, effective 33.6%, invalid 6.3%. (3) Adverse reactions to abdominal pain and discomfort were 10.1%. After adjusting the dose disappeared. Conclusions The initial dosage of oral lactulose solution for senile constipation is 15 ~ 30ml / d. Is to increase the frequency of defecation 3 / day or more, fecal material soft, the total amount of total effective, the total effective rate was 93.7%.