A neural-network-based motion controller in task space is presented in this paper. The proposed controller is addressed as a two-loop cascade control scheme. The outer loop is given by kinematic control in the task space. It provides a joint velocity reference signal to the inner one. The inner loop implements a velocity servo loop at the robot joint level. A radial basis function network (RBFN) is integrated with proportional-integral (PI) control to construct a velocity tracking control scheme for the inner loop. Finally, a prototype technology based control system is designed for a robotic manipulator. The proposed control scheme is applied to the robotic manipulator. Experimental results confirm the validity of the proposed control scheme by comparing it with other control strategies.