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中枢性睡眠呼吸暂停由控制呼吸肌运动的中枢神经系统传出受抑所致。现对明显中枢源性上呼吸道完全梗阻的睡眠呼吸暂停进行研究。观察4例病人,其中3例出现近1分钟与经鼻正压呼吸有关的睡眠呼吸暂停。第一例病人为女性,26岁,患先天性肌病伴呼吸衰竭及心力衰竭。给经鼻间歇性正压呼吸。呼吸器调到20升/分、频率25次/分。睡眠开始后数分钟病人进入第二阶段非快速眼动睡眠(non-rapideye-movement sleep)。观察到发作性深度氧去饱和状态,从95%到60%。多种波动描记仪显示了这样的发作,胸廓运动停止近1分钟,
Central sleep apnea is caused by suppression of the central nervous system that controls respiratory muscle movement. Sleep apnea is now clearly marked with central obstructed upper respiratory tract obstruction. Four patients were observed. Three of them developed apnea related to nasal positive pressure breathing for nearly 1 minute. The first patient was a woman, aged 26, with congenital myopathy with respiratory failure and heart failure. Give nasal intermittent positive pressure breathing. Respirator transferred to 20 l / min, the frequency of 25 beats / min. The patient enters the second phase of non-rapideye-movement sleep within minutes after their onset of sleep. Episodic depth oxygen desaturation was observed from 95% to 60%. A variety of angiographs showed such episodes, with the thorax motion stopped for nearly 1 minute,