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皮肤T淋巴细胞瘤 (CTCL)早期在临床和病理上诊断均有一定难度 ,组织学上改变常为非特异性 ,淋巴细胞异型性和亲表皮性可不明显甚至没有。用PCR法检测出克隆性T细胞受体γ基因重排是皮肤T细胞淋巴瘤的标志。为了进一步评价组织学方法以及TCR基因重排分析的诊断价值
Skin T-cell lymphoma (CTCL) in the early clinical and pathological diagnosis are difficult, histological changes often non-specific, lymphocyte atypia and pro-epidermal sex may not even apparent. Detection of clonal T cell receptor gamma gene rearrangements by PCR is a hallmark of cutaneous T-cell lymphoma. In order to further evaluate the diagnostic value of histological methods and TCR gene rearrangement analysis