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目的:探讨2型糖尿病患者合并冠心病与踝臂指数(ABI)的相关性及糖尿病并发冠心病的危险因素。方法:选择2008年1月至2008年7月在新疆医科大学第五附属医院内分泌科住院的所有糖尿病患者,共269例,男158例,女111例。按有无冠心病分为冠心病组(54例)和无冠心病组(215例)。所有患者均记录生活方式,查体质指数(BMI)、心电图,测血压、血脂、空腹血糖(FBG)、餐后2 h血糖(PBG)、糖化血红蛋白(HbA1C)、C反应蛋白(CRP)。并于入院3d内行ABI测定,同时进行Logistic冠心病多因素分析。结果:(1)合并冠心病组ABI的敏感性及特异性分别为77.8%、93.5%;(2)多因素分析表明ABI降低(OR=0.421,P=0.025)、BMI≥25(OR=1.148,P=0.007)、收缩压(OR=1.035,P=0.000)、总胆固醇水平升高和颈动脉斑块是冠心病的危险因素。结论:测定ABI能提高冠心病的诊断率。
Objective: To investigate the correlation between coronary heart disease and ankle brachial index (ABI) in type 2 diabetic patients and the risk factors of diabetes complicated with coronary heart disease. Methods: From January 2008 to July 2008 in Urology Hospital, Fifth Affiliated Hospital of Xinjiang Medical University, all diabetic patients, a total of 269 cases, 158 males and 111 females. Coronary heart disease was divided into coronary heart disease group (54 cases) and no coronary heart disease group (215 cases). All patients recorded life style, BMI, ECG, blood pressure, blood fat, fasting blood glucose (FBG), 2 h postprandial blood glucose (PBG), HbA1C and CRP. ABI was performed within 3 days after admission, and multivariate Logistic coronary disease was also performed. Results: (1) The sensitivity and specificity of ABI in patients with coronary heart disease were 77.8% and 93.5% respectively. (2) Multivariate analysis showed that ABI was lower (OR = 0.421, P = 0.025) , P = 0.007), systolic blood pressure (OR = 1.035, P = 0.000), elevated total cholesterol levels and carotid artery plaque were the risk factors for coronary heart disease. Conclusion: The determination of ABI can improve the diagnosis of coronary heart disease.