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本文综述了近年来三尖杉酯碱类生物碱的药化、药理、药物动力学及临床应用等方面的研究进展,并介绍了此类药物抗肿瘤作用的新机理——对肿瘤细胞诱导分化作用的研究及其在临床上的应用。
This review summarizes the recent advances in the pharmacodynamics, pharmacology, pharmacokinetics and clinical applications of harringtonine alkaloids, and introduces the new mechanism of anti-tumor effect of these drugs - the induction of differentiation of tumor cells The role of research and its clinical application.