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目的探讨宫腔镜术治疗黏膜下子宫肌瘤对卵巢储备功能的影响。方法选取2011年3月-2015年12月深圳市宝安区福永人民医院接受宫腔镜术治疗的195例黏膜下子宫肌瘤患者为研究对象,根据荷兰Haarlem国际宫腔镜学会提出的分类标准将上述患者分为3组,A组65例,均为O型黏膜下子宫肌瘤,B组69例,均为Ⅰ型黏膜下子宫肌瘤,C组61例,均为Ⅱ型黏膜下子宫肌瘤。对比分析上述3组患者手术前后血清性激素水平以及阴道彩超指标。结果手术前,3组患者血清LH、FSH、E2、T、P相比及术后6个月,组内比较显示3组血清LH、FSH、E2、T、P与手术前相比差异均无统计学意义(P>0.05)。手术前,3组患者PI、PSV、RI、Fo相比差异无统计学意义(P>0.05)。手术后3组阴道彩超组间比较显示3组之间PI、PSV差异有统计学意义(P<0.05)。结论宫腔镜术治疗3种类型黏膜下子宫肌瘤均不影响其卵巢储备功能,但是对Ⅰ型、Ⅱ型黏膜下子宫肌瘤患者的卵巢血供则有一定程度的影响。
Objective To investigate the effect of hysteroscopic treatment of submucosal uterine fibroids on ovarian reserve. Methods From March 2011 to December 2015, 195 cases of submucous myoma of uterus treated by hysteroscopy in Fuyong People’s Hospital of Bao’an District of Shenzhen City were selected as research objects. According to the classification criteria proposed by Haarlem International Hysteroscopy Society The above patients were divided into 3 groups, A group of 65 cases, all of O-submucosal uterine fibroids, B group 69 cases, all type Ⅰ submucosal uterine fibroids, C group, 61 cases were type Ⅱ submucosal uterine muscle tumor. The levels of serum sex hormones and vaginal ultrasound before and after surgery were compared between the three groups. Results Before operation, the levels of serum LH, FSH, E2, T, P in 3 groups and 6 months after operation showed no significant difference in LH, FSH, E2, T, P, Statistical significance (P> 0.05). There was no significant difference in PI, PSV, RI and Fo between the three groups before surgery (P> 0.05). The postoperative three groups of vaginal ultrasound group comparison showed that between the three groups PI, PSV difference was statistically significant (P <0.05). Conclusion Hysteroscopic treatment of 3 types of submucosal uterine fibroids does not affect their ovarian reserve, but the type Ⅰ and type Ⅱ submucosal uterine fibroids in patients with ovarian blood supply to a certain extent.