论文部分内容阅读
目的探讨声触诊组织量化(VTQ)技术在乳腺肿块良恶性鉴别诊断中的应用价值。方法应用VTQ技术对102例共107个乳腺肿块内部、肿块边缘及周围乳腺组织行剪切波速度(SWV)测量,分别记为SWVi、SWVb、SWVg。以病理结果为标准,比较乳腺良性组与恶性组SWV差异,绘制ROC曲线确定判断乳腺病灶良恶性的最佳界值。结果所有肿块的SWVi值明显高于SWVb和SWVg,SWVb值明显高于SWVg,差异均有统计学意义(P<0.01)。乳腺恶性组SWVi、SWVb分别为(6.70±1.75)、(4.58±1.38)m/s,良性组分别为(3.52±1.52)、(2.80±0.97)m/s,两组参数恶性组均高于良性组(P<0.01)。以SWVi值5.06m/s为界值诊断乳腺肿块良恶性的敏感性为83.7%、特异性为85.9%;以SWVb值3.51m/s为界值诊断肿块良恶性的敏感性为79.1%、特异性为81.2%。结论乳腺肿块内部与肿块边缘的SWV均有助于乳腺肿块良恶性的鉴别诊断。
Objective To investigate the value of VTQ in the differential diagnosis of benign and malignant breast tumors. Methods VTQ technique was used to measure the shear wave velocity (SWV) of 102 breast masses in 107 breast masses, the edge of the tumor and the surrounding breast tissue, and were respectively recorded as SWVi, SWVb and SWVg. According to pathological results, the difference of SWV between benign and malignant breast tissues was compared. The ROC curve was drawn to determine the best cutoff value for judging benign and malignant breast lesions. Results The SWVi values of all the masses were significantly higher than those of SWVb and SWVg, and the SWVb values were significantly higher than those of SWVg (all P <0.01). The SWVi and SWVb of breast malignant group were (6.70 ± 1.75) and (4.58 ± 1.38) m / s, respectively, and those in benign group were (3.52 ± 1.52) and (2.80 ± 0.97) m / Benign group (P <0.01). The sensitivity and specificity of diagnosing benign and malignant breast tumors with SWVi value of 5.06 m / s were 83.7% and 85.9%, respectively. The sensitivity of diagnosing benign and malignant tumors with SWVb value of 3.51 m / s was 79.1% Sex is 81.2%. Conclusion SWV in the breast mass and the margins of the mass can be helpful for the differential diagnosis of benign and malignant breast masses.