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【目的】探讨板层小体对预测早产儿肺成熟度的临床价值。【方法】对早产儿进行板层小体计数,找出反应肺成熟度的判定界值,并统计其对肺成熟度的阳性预测值、阴性预测值、敏感性、特异性以及对34周以下早产儿的预测情况。【结果】成熟判定界值≥98 000/μL时其阴性预测值100%;阳性预测值27.1%;敏感性100%;特异性41.9%;34周以下早产儿的阴性预测值100%,阳性预测值53.6%,敏感性100%,特异性23.5%,可以避免23.5%早产儿气管插管和使用PS;不成熟判定界值≤33 000/μL时阴性预测值96.7%;阳性预测值46.7%;敏感性87.5%;特异性78.4%;34周以下早产儿的阴性预测值85.7%,阳性预测值72%,敏感性100%,特异性70.6%;可使70.6%的早产儿避免气管插管和肺表面活性物质使用;33 000～98 000/μL之间为可疑值时此范围的发病率为20%。【结论】板层小体的计数对于预测新生儿肺成熟度是一个较好的筛选试验。
【Objective】 To investigate the clinical value of lamellar bodies in predicting lung maturation in preterm infants. 【Method】 The platelet body count of preterm infants was used to find out the judgment threshold value of the reactionary lung maturity, and the positive predictive value, negative predictive value, sensitivity, specificity of the maturity of the lung were calculated. Predictors of premature babies. 【Results】 The negative predictive value was 100%, the positive predictive value was 27.1%, the sensitivity was 100%, the specificity was 41.9%, and the negative predictive value was 100%, the positive predictive value was less than 34 weeks Value of 53.6%, sensitivity of 100%, specificity of 23.5%, 23.5% of premature infants can avoid tracheal intubation and the use of PS; immature judgment cutoff value of ≤33000 / μL negative predictive value of 96.7%; positive predictive value of 46.7% The sensitivity was 87.5%; the specificity was 78.4%. The negative predictive value of preterm infants under 34 weeks was 85.7%, the positive predictive value was 72%, the sensitivity was 100% and the specificity was 70.6%. 70.6% of premature infants were prevented from intubation and Pulmonary surfactant use; in the range of 33 000 to 98 000 / μL suspicious values the incidence of this range is 20%. 【Conclusion】 The counting of lamellar bodies is a good screening test for predicting lung maturation in newborns.