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目的：探讨完全腹腔镜下脾切除、贲门周围血管离断术治疗门静脉高压症的安全性与可行性。方法对30例完全腹腔镜下脾切除、贲门周围血管离断术与30例开腹脾切除、贲门周围血管离断术的临床资料进行对比研究。结果完全腹腔镜下脾切除、贲门周围血管离断术在住院时间、住院费用、手术出血量、肠道功能恢复时间、术后并发症等方面优于开腹脾切除、贲门周围血管离断术。结论完全腹腔镜下脾切除、贲门周围血管离断术是安全可行的。“,”Objective To explore the safety and feasibility of total laparoscopic splenectomy plus pericardial devascularization for portal hypertension.Methods The clinical data of 30 cases of total lapa-roscopic splenectomy plus pericardial devascularization and 30 cases of open surgery were compared.Re-sults Total laparoscopic splenectomy plus pericardial devascularization is better than open surgery in hos-pital stay,hospitalization cost,operation time,intraoperative bleeding,postoperative intestinal function re-covery and postoperative complications.Conclusion Total laparoscopic splenectomy plus pericardial de-vascularization is safe and feasible.