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目的:比较特布他林不同给药方式在妊娠合并哮喘中的效果。方法:选取2006年1月～2010年1月于该院进行治疗的70例妊娠合并哮喘的患者为研究对象,将其随机分为A组(特布他林雾化吸入组)35例和B组(特布他林口服组)35例,后将两组患者的治疗总有效率、不良反应发生率、咳嗽、喘息、哮鸣音消失时间及治疗前后的FEV 1%、FVC、PaO2及PaCO2水平进行统计及比较。结果:A组的治疗总有效率高于B组,不良反应发生率低于B组,咳嗽、喘息、哮鸣音消失时间短于B组,FEV 1%、FVC、PaO2及PaCO2水平优于B组,P<0.05或P<0.01,有统计学差异。结论:特布他林雾化吸入治疗妊娠合并哮喘的临床效果优于口服给药,安全性也较高,综合优势明显。
OBJECTIVE: To compare the effects of different administrations of terbutaline in asthma with gestational age. Methods: Seventy patients with pregnancy-induced asthma who were treated in our hospital from January 2006 to January 2010 were randomly divided into group A (35 cases in group A) and group B 35 patients in group (oral group of terbutaline), the total effective rate of treatment, the incidence of adverse reactions, the disappearance time of cough, wheezing, wheeze and the FEV 1%, FVC, PaO 2 and PaCO 2 before and after treatment Level statistics and comparison. Results: The total effective rate of treatment group A was higher than that of group B, the incidence of adverse reactions was lower than that of group B, the disappearance time of cough, wheezing and wheeze was shorter than that of group B, FEV 1%, FVC, PaO2 and PaCO2 were better than B Group, P <0.05 or P <0.01, with statistical difference. Conclusion: Terbutaline nebulization is superior to oral administration in the treatment of asthma complicated with pregnancy, and its safety is also high. The comprehensive advantages are obvious.