论文部分内容阅读
目的探讨血清缺血修饰白蛋白(IMA)与心肌型脂肪酸结合蛋白(H-FABP)联合检测在急性心肌梗死(AMI)患者中的临床意义。方法以急性胸痛患者90例为研究对象,检测血清IMA、H-FABP,根据AMI诊断标准分为AMI患者、非AMI患者,计算IMA、H-FABP及IMA+H-FABP对AMI诊断的诊断性试验评价指标。结果 AMI患者血清IMA、H-FABP明显高于非AMI患者及正常对照组(P<0.01);IMA、H-FABP、IMA+H-FABP诊断AMI的敏感度分别为:89.5、93.7、100。特异度分别为:73.8、80.9、71.4。阴性预期值分别为:86.1、91.8、100。阳性预期值分别为:79.6、84.9、80。结论 IMA、H-FABP是诊断AMI的敏感指标,两者联合检测对AMI诊断价值更优。
Objective To investigate the clinical significance of combined detection of serum ischemic-modified albumin (IMA) and cardiac fatty acid binding protein (H-FABP) in patients with acute myocardial infarction (AMI). Methods 90 cases of acute chest pain were selected as the object of study. Serum IMA and H-FABP were measured. According to AMI diagnostic criteria, they were divided into AMI patients and non-AMI patients. The diagnostic value of IMA, H-FABP and IMA + H-FABP in diagnosis of AMI Test evaluation index. Results The serum levels of IMA and H-FABP in AMI patients were significantly higher than those in non-AMI patients and normal controls (P <0.01). The sensitivity of IMA, H-FABP and IMA + H-FABP in diagnosing AMI were 89.5 and 93.7,100, respectively. Specificity were: 73.8,80.9,71.4. Negative expected values were: 86.1,91.8,100. Positive expected values were: 79.6,84.9,80. Conclusions IMA and H-FABP are sensitive indicators for the diagnosis of AMI, and the combined detection of them is more valuable in the diagnosis of AMI.