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目的探讨肺曲霉菌球的临床特点、手术治疗的安全性与疗效。方法回顾分析16例采用外科手术治疗的肺曲霉菌病的临床资料和随访结果。结果共行肺叶切除术4例,局部切除术12例,切除标本送检,均证实为肺曲霉菌病,术后行抗真菌治疗2~4周。全组无手术死亡,术后发生曲霉菌胸腔播散2例。随访4个月~9年无肺曲霉病复发和播散。结论手术治疗肺曲霉菌球安全、有效,一旦确诊应积极手术治疗。
Objective To investigate the clinical characteristics of pulmonary aspergillus spores, surgical treatment of the safety and efficacy. Methods The clinical data and follow-up results of 16 cases of pulmonary aspergillosis treated by surgery were retrospectively analyzed. Results Common lobectomy was performed in 4 cases, local excision in 12 cases and resection of the specimens were all confirmed as pulmonary aspergillosis. The patients were treated with antifungal therapy for 2 to 4 weeks. All patients died without surgery, aspergillus pleural disseminated in 2 cases. Follow-up 4 months to 9 years without pulmonary aspergillosis recurrence and dissemination. Conclusion Surgical treatment of pulmonary aspergillus ball safe and effective, once the diagnosis should be positive surgical treatment.