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目的 观察中药益髓生血灵治疗重型β-珠蛋白生成障碍性贫血的临床疗效。方法 重型β-珠蛋白生成障碍性贫血27例,重型β-珠蛋白生成障碍性贫血复合血红蛋白E13例,益髓生血灵每日3次,每次10g,3个月为1疗程,治疗前后检测血红蛋白(Hb)、红细胞(RBC)、网织红细胞(Ret)和抗碱血红蛋白(HbF)。结果 22例重型β-珠蛋白生成障碍性贫血和13例重型β-珠蛋白生成障碍性贫血复合血红蛋白E患儿治疗有效,治疗前后患儿Hb、RBC、Ret和HbF差异均有统计学意义(P<0.001)。结论 益髓生血灵治疗重型β-珠蛋白生成障碍性贫血有一定疗效。
Objective To observe the clinical efficacy of Yisu Shengyinling in treating severe β-globin aplasia. Methods Severe β-globin aplastic anemia in 27 cases, severe β-globin aplastic anemia complex hemoglobin E13 cases, Yisheng Ssangyong 3 times a day, each 10g, 3 months for a course of treatment before and after treatment Hemoglobin (Hb), red blood cells (RBC), reticulocytes (Ret) and anti-alkali hemoglobin (HbF). Results Twenty-two patients with severe β-globin aplastic anemia and 13 patients with severe β-globin aplastic anemia complicated with hemoglobin E were effective in treatment. The differences of Hb, RBC, Ret and HbF in children before and after treatment were statistically significant ( P <0.001). Conclusion Yi Su Sheng Xue Ling treatment of severe β-globin aplastic anemia have a certain effect.