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随着人类平均寿命的延长,实体肿瘤对人类的危害日益突出,致死率高,尽管新的抗癌药物和化疗方案不断推出,化疗仍然是治疗肿瘤的重要手段之一。化疗药物的非针对性治疗及肿瘤的耐药性(MDR)常导致化疗的失败,并产生严重的毒副反应。中药丹参具有活血化瘀和抗肿瘤作用,临床上也有丹参配合化疗达到增效减副作用的报道。本实验中,我们将丹参联合5-Fu对Lewis肺癌小鼠进行实验,观察丹参的增效减副作用。
With the extension of average life expectancy of human beings, solid tumors have become increasingly harmful to human beings and have a high lethality rate. Although new anticancer drugs and chemotherapy regimens continue to be introduced, chemotherapy remains an important means of treating tumors. Non-targeted treatment of chemotherapy drugs and tumor resistance (MDR) often lead to the failure of chemotherapy, and have serious side effects. Salvia with traditional Chinese medicine has the role of promoting blood circulation and anti-tumor, clinically Salvia combined with chemotherapy to reduce the side effects of synergistic reports. In this experiment, we will Salvia joint 5-Fu mice Lewis lung cancer experiments to observe the efficiency of Salvia side effects.