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目的探讨血清降钙素原(PCT)检测在急性胰腺炎(AP)早期诊断的临床意义。方法将AP患者分为轻型(MAP)急性水肿型35例和重型(SAP)急性出血坏死型20例2组,另设正常对照组健康体检者30例,检测并比较各组血清PCT浓度水平。结果 55例AP患者血清PCT浓度较正常对照组明显上升,差异有统计学意义(P<0.05),在治疗过程中,(1-7 d内),MAP患者血清PCT水平有不同程度下降,而SAP患者血清PCT水平呈逐步升高的趋势。结论检测AP患者治疗前后的PCT,对SAP早期的预测和指导治疗及改善预后有着重要意义。
Objective To investigate the clinical significance of serum procalcitonin (PCT) detection in the early diagnosis of acute pancreatitis (AP). Methods AP patients were divided into two groups: acute edematous type (MAP) and acute hemorrhagic necrosis type (SAP) type and acute necrotic type (20 cases). Another 30 healthy volunteers were enrolled in the control group. The levels of serum PCT were detected and compared. Results Serum PCT concentrations in 55 patients with AP were significantly higher than those in the control group (P <0.05). During the course of treatment (within 1-7 days), serum PCT levels in MAP patients decreased to some extent, The level of serum PCT in PCT patients showed a gradual increase trend. Conclusion The detection of PCT before and after treatment of AP patients is of great significance for the early prediction and treatment of SAP and the improvement of prognosis.