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目的分析疑似布鲁杆菌病患者血清学实验室检测结果及主要临床表现等特点,为临床诊断提供依据。方法采用WS 269—2007《布鲁氏菌病诊断标准》的RBPT、SAT 2种方法对疑似布鲁杆菌病患者血清进行检测,分析检测结果。结果共检测疑似患者1 897例,RBPT、SAT阳性率分别为27.89%、22.88%,2种方法的阳性吻合率为82.04%;感染主要集中在40岁~、50岁~年龄组,男、女性别比为4.56∶1,不同年龄、性别阳性率差异均有统计学意义(P<0.01);434份阳性标本中,无明显接触史的占10.60%,有明显接触史的占89.40%(388/434);患者多以发热(80.87%)、出汗(55.76%)、乏力(50.46%)为主。结论临床诊断要综合接触史、临床表现以及实验室检测结果进行诊断。
Objective To analyze the serological laboratory test results and major clinical manifestations of suspected brucellosis patients and provide the basis for clinical diagnosis. Methods The RBPT and SAT of WS 269-2007 Diagnostic Criteria of Brucellosis were used to detect the serums of suspected brucellosis patients and the test results were analyzed. Results A total of 1 897 suspected patients were detected. The positive rates of RBPT and SAT were 27.89% and 22.88% respectively. The positive coincidence rates of the two methods were 82.04%. The prevalence of infection was mainly between 40 and 50 years old, male and female (P <0.01). In 434 positive specimens, there was no significant history of exposure, accounting for 10.60% and 89.40% (388%) with obvious history of exposure / 434). The patients were mostly fever (80.87%), sweating (55.76%) and weakness (50.46%). Conclusion Clinical diagnosis should be based on a comprehensive history of exposure, clinical manifestations and laboratory test results.