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脑胶质瘤约占脑肿瘤总数的1/3,现有治疗包括手术切除、放射治疗与各种化学治疗的结果仍不能令人满意。1958年有人报告对神经外胚层及中胚层的脑瘤可用细胞抑制剂治疗。近年来,神经外科医师基于以下两点对脑瘤的化学治疗发生了兴趣,第一,脑部深在的恶性胶质瘤一般不适于外科治疗;第二,化学治疗已能治疗一些脑外肿瘤。胶质瘤的生物学特征胶质瘤呈浸润性生长,病理学所见常比
Gliomas account for about 1/3 of the total number of brain tumors, and the results of current treatments including surgical resection, radiation therapy, and various chemical treatments are still unsatisfactory. In 1958, it was reported that brain tumors of the neuroectoderm and mesoderm could be treated with cytostatic agents. In recent years, neurosurgeons have become interested in the chemotherapy of brain tumors based on the following two points. First, malignant brain gliomas are generally not suitable for surgical treatment; second, chemotherapy has been able to treat some brain tumors . The biological features of gliomas Infiltrating gliomas, often seen in pathology