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目的探讨不同模式经直肠超声前列腺穿刺活检对前列腺癌(prostate cancer,PCA)Gleason评分的影响。方法对95例已确诊的PCA进行回顾性研究,不同模式的经直肠前列腺穿刺活检共4组,即系统穿刺活检组(SB组)28例,仅行对比增强靶向活检组(CEUS组)15例,仅行弹性成像靶向活检组(UE组)28例,CEUS联合UE靶向活检组(CUES+UE组)24例。将得到的Gleason评分进行组间比较。结果 SB组与CEUS组之间、CEUS组与UE组间、CEUS+UE组两两之间的差异均无统计学意义(P>0.05),而UE组、CUES+UE组与SB组的Gleason评分的差异均有统计学意义(P<0.05)。结论与经直肠超声引导下前列腺系统活检相比,经直肠超声弹性成像技术、经直肠对比增强超声联合超声弹性成像技术引导的前列腺靶向活检有助于得到较高的前列腺组织Gleason评分。
Objective To investigate the effect of different modes of transrectal ultrasound prostate biopsy on Gleason score of prostate cancer (PCA). Methods A total of 95 confirmed PCA cases were retrospectively studied. There were 4 transrectal prostatic biopsies in 28 different types of biopsy samples of the biopsy group (SB group) For example, there were 28 cases in the elastography targeted biopsy group (UE group) and 24 cases in the CEUS combined with UE targeted biopsy group (CUES + UE group). The Gleason scores obtained were compared between groups. Results There was no significant difference between SBUS group and CEUS group, between CEUS group and UE group, CEUS + UE group (P> 0.05), while between UE group, CUES + UE group and SB group Gleason There were significant differences in scores (P <0.05). Conclusion Compared with transrectal ultrasound-guided prostate biopsy, transrectal ultrasound elastography and transrectal contrast-enhanced ultrasound combined with elastography in prostate biopsy can help to obtain higher Gleason score of prostate tissue.